t(14;20)(q32;q12) IGH/MAFB in Plasma Cell Myeloma
نویسندگان
چکیده
منابع مشابه
Plasma cell myeloma
Myeloma is the most common neoplasm of bone.The majority is diagnosed with a bone marrow aspirate, rather than a bone biopsy. Most patients have disseminated disease, associated with a poor prognosis. Some have solitary myeloma with a more favourable clinical course but eventually, most become multifocal. A small percentage of patients have sclerotic bone lesions, which may be associated with p...
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Orbital plasma cell myeloma is a rare condition. In a review of 222 intraorbital tumours, Forrest (1949) found only one case, and Offret (I951) reported two cases in a series of 676 orbital tumours. Clarke (I 953) emphasized the differentiation between the plasma cell myeloma of myelomatosis and the benign plasma cell tumour produced by chronic inflammation. The present report concerns a case p...
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abstract: plasma cellmyeloma constitutes about 10% of all hematologicmalignancies. metastatic cutaneous lesions without underlying bony involvement are rare and associated with advanced disease, poor prognosis and high tumor burden. igg is the most common subtype and igd is believed to have a more aggressive course.######
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Plasma cell myeloma is a clinically heterogeneous malignancy accounting for approximately one to 2% of newly diagnosed cases of cancer worldwide. Treatment options, in addition to long-established cytotoxic drugs, include autologous stem cell transplant, immune modulators, proteasome inhibitors and monoclonal antibodies, plus further targeted therapies currently in clinical trials. Whilst treat...
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A 66-year-old man presented to the emergency department with weakness and back pain. Remarkable laboratory results included a hemoglobin of 6.1 g/dL (13.5–17.5 g/dL) and creatinine of 17.3 mg/dL (0.6–1.3 mg/dL). Serum protein electrophoresis showed a gamma paraprotein spike demonstrated by immunofixation to be IgG lambda. Serum free lambda light chains were markedly elevated at 11,160 mg/L (5.7...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2019
ISSN: 1768-3262
DOI: 10.4267/2042/70482